ABSTRACT
This research systematically analyzes the effects that global megatrends, digitalizing economy, and the continuing COVID-19 pandemic are having on the transformation of professional career management and changing professional skills for achieving career purposes and tasks, providing a competent approach to the labor market. It also suggests a sustainable career management process for people to prepare career goals, objectives, and ambitions in the rapidly evolving digital landscape. Following this aim, the secondary analysis of the literature reviewed aided in offering important information to satisfy the original research targets and aims. Thus, the study maintained an exploratory and deductive research design to analyze the qualitative data gathered on the phenomenon of professional career management under the digital transformation in Asian countries. The analysis reveals that some megatrends have transformed how professional career development occurs. This paper is novel because it provides a critical assessment of the global megatrends and the impact of the digital economy related to professional career management transformation, with specific emphasis on Asian countries during the COVID-19 pandemic. Thus, the paper redounds the extant literature, making a significant contribution to the current debate in the literature. Additionally, it is expected to contribute to the sustainable development of the labor market in Asian countries based on system research and converging the concepts of transformation processes in professional career management affected by megatrends with theoretical and methodological support.
ABSTRACT
BackgroundDeep venous thrombosis (DVT) is a severe complication of the coronavirus disease 2019 (COVID-19). It may interfere with COVID-19 treatment and delay the recovery, but there is less data about the anticoagulant therapy and sex difference of VTE in patients with COVID-19. The purpose of this study is to study the prevalence, risk factors, anticoagulant therapy and sex difference of deep venous thrombosis (DVT) in patients with COVID-19.MethodsThe enrolled 121 patients were confirmed positive for COVID-19. All suspected patients with a high Caprini index (≥4) or PADUA index (≥4) received color Doppler Ultrasound (US) to screen DVT in both lower extremities. Clinical characteristics of DVT-COVID-19 patients were analyzed. Multivariate logistic regression was performed to identify risk factors related to DVT in COVID-19 patients. The distribution of DVT locations, anticoagulation therapy with sex difference, and the outcomes were also analyzed.ResultsDVT was found in 48% asymptomatic COVID-19 patients with increased PAUDA index or Caprini index by US scanning. Multivariate logistic regression determined that age, CRP and baseline D-dimer were risk factors among COVDI-19 patients. Although the most common DVT location was infrapopliteal (Class I and Class II), higher mortality in DVT-COVID-19 patients was confirmed. DVT-COVID-19 patients presented significant increases in the CRP, neutrophil count and D-dimer throughout the whole inpatient period compared to non-DVT-COVID-19 patients. Although anticoagulation therapy accelerated the recovery of lymphocytopenia condition in DVT patients, men DVT-COVID-19 patients showed higher CRP and neutrophil count vs. lymphocyte count (N/L) ratio but lower lymphocyte count compared to women DVT-COVID-19 patients. ConclusionsDVT is common in COVID-19 patients with high risk factors, especially for older age, higher CRP and baseline D-dimer populations. It is important to consider sex differences in the anticoagulant therapy among DVT-COVID-19 patients.